Background on the biology and diseases that underpin our research at EpiCENTR.
The stem cell population of the respiratory epithelium — how they maintain, repair and regenerate the airway lining, and why they are central to lung health and disease.
Read more →How this rare genetic disorder affects the airway in children, causing life-threatening laryngotracheal stenosis, and our work towards a cell and gene therapy approach.
Read more →Air–liquid interface cultures and organoid systems for studying the airway epithelium outside the body — what these models can and cannot tell us.
Read more →The biological rationale for repairing diseased airway epithelium at the cellular level, the challenges of ex vivo expansion and delivery, and the current state of the field.
Read more →Why epithelial repair matters in conditions including COPD, cystic fibrosis, primary ciliary dyskinesia, and viral infection — and what regenerative medicine might offer.
Read more →